PROBLEM TO BE SOLVED: To provide a composition for the inhibition of pulmonary fibrosis by inhibiting macrophage proliferation/differentiation or promoting macrophage aging.;SOLUTION: The present invention provides a composition for promoting macrophage aging in fibrosis regions, comprising Sphingosine-1-phosphate receptor-2 (S1 P2) antagonist as an active ingredient.;SELECTED DRAWING: None;COPYRIGHT: (C)2017,JPO&INPIT
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机译:解决的问题:提供一种通过抑制巨噬细胞增殖/分化或促进巨噬细胞衰老来抑制肺纤维化的组合物;解决方案:本发明提供一种用于在纤维化区域促进巨噬细胞衰老的组合物,其包含鞘氨醇-1-磷酸受体-2(S1 P 2 Sub>)拮抗剂作为有效成分。;部分提要:无;版权:(C)2017,JPO&INPIT
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