Modelling Disease Progression and Intervention Effects Using Non-Clinical Information Proxies for Clinical Information

摘要

Modelling disease progression using non-clinical information proxies for clinical information, by accessing a computer-based Bayesian model of the progression of a disease, adapting the Bayesian model to include one or more clinical factors that are believed to influence progression of the disease, adapting the Bayesian model to include one or more non-clinical proxies for one or more clinical factors that are believed to influence progression of the disease, identifying interdependencies among variables of the Bayesian model based on a meta-analysis of literature associated with any of the disease, the clinical factors, and the non-clinical proxies, providing values for any of the variables of the Bayesian model, and presenting any portion of the Bayesian model via a computer-based output device.