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Smartphone compatible on-chip biodetection using integrated optical component and microfluidic channel with nanopillar array

机译:使用集成的光学组件和具有纳米柱阵列的微流体通道,与智能手机兼容的片上生物检测

摘要

Methods, apparatuses, and computer program products are provided where fluid, such as a blood sample, is entered into a microfluidic channel in a microchip where the microfluidic channel possesses a micro/nanopillar array for sorting molecules by size. When the fluid passes through the micro/nanopillar array it is separated into particles of interest or particles not of interest or both. When particles of interest are lit by a light source via a first waveguide in the microchip connecting the light source to the microfluidic channel, then lighted particles of interest can be detected by an optical detector via a second waveguide in the microchip connecting the optical detector to the microfluidic channel. The information from the optical detector can be analyzed further by connecting the microchip to a mobile computing device with its own processing abilities or abilities via the internet or cloud.
机译:提供了方法,装置和计算机程序产品,其中将诸如血液样本的流体输入微芯片中的微流体通道,其中微流体通道具有用于按大小分选分子的微/纳米柱阵列。当流体通过微/纳米柱阵列时,它被分成感兴趣的颗粒或不感兴趣的颗粒或两者。当感兴趣的粒子由光源通过将光源连接到微流体通道的微芯片中的第一波导照亮时,则可以通过光学检测器通过将光检测器与光检测器相连的第二芯片中的第二波导来检测被照亮的感兴趣颗粒。微流体通道。通过将微芯片连接到具有自己的处理能力或经由互联网或云的能力的移动计算设备,可以进一步分析来自光学检测器的信息。

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