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METHODS FOR PREDICTING THE RADIOSENSITIVITY OF A CANCER TUMOR AND METHODS OF TREATING CANCER

机译:肿瘤放射敏感性的预测方法和癌症的治疗方法

摘要

Methods for predicting the radiosensitivity of a cancer tumor and treating cancer in a subject are provided. In another aspect, methods of treating cancer in a subject are also provided. The methods may include administering to the subject radiation therapy based on the expression level of no more than 35, 30, 25, 20, 15, 10, or 5 biomarkers in a tumor sample from the subject. The methods of treating cancer in a subject may also include administering a therapeutically effective amount of a FAS agonist and/or a TNFRSF10B agonist to the subject, and administering radiation therapy to the subject.
机译:提供了预测癌症肿瘤的放射敏感性和治疗受试者中的癌症的方法。在另一方面,还提供了治疗受试者癌症的方法。所述方法可包括基于来自受试者的肿瘤样品中不超过35、30、25、20、15、10或5个生物标志物的表达水平对受试者进行放射治疗。在受试者中治疗癌症的方法还可包括对受试者施用治疗有效量的FAS激动剂和/或TNFRSF10B激动剂,以及对受试者进行放射治疗。

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