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Broadly Neutralizing Monoclonal Antibodies Against HIV-1 V1V2 Env Region

机译:针对HIV-1 V1V2 Env地区的广泛中和单克隆抗体

摘要

The present invention relates anti-HIV therapies and prophylaxis. Specifically, the invention relates to broadly neutralizing antibodies against HIV-1, nucleic acids encoding these antibodies, vectors comprising the nucleic acids and cells and pharmaceutical compositions Comprising said vectors and/or antibodies. The present invention also relates to use of the antibodies and/or vectors for the treatment and/or prevention of HIV-1 infection in a subject. Furthermore, the invention also relates to a kit containing the antibodies of the invention.
机译:本发明涉及抗HIV疗法和预防。具体地,本发明涉及针对HIV-1的广泛中和抗体,编码这些抗体的核酸,包含该核酸和细胞的载体以及包含所述载体和/或抗体的药物组合物。本发明还涉及抗体和/或载体在治疗和/或预防受试者中HIV-1感染中的用途。此外,本发明还涉及包含本发明抗体的试剂盒。

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