首页> 外国专利> METHOD, COMPUTER SYSTEM AND SOFTWARE FOR SELECTING TAG SNP, AND DNA MICROARRAY EQUIPPED WITH NUCLEIC ACID PROBE CORRESPONDING TO TAG SNP SELECTED BY SAID SELECTION METHOD

METHOD, COMPUTER SYSTEM AND SOFTWARE FOR SELECTING TAG SNP, AND DNA MICROARRAY EQUIPPED WITH NUCLEIC ACID PROBE CORRESPONDING TO TAG SNP SELECTED BY SAID SELECTION METHOD

机译:标记SNP的选择方法,计算机系统和软件,以及与所述选择方法选择的标记SNP相对应的核酸探针配备的DNA微阵列

摘要

The present invention provides a selection method of tag SNPs, for constituting a group of nucleic acid probes corresponding to the tag SNPs, the tag SNPs being used for performing imputation of information on SNPs of human genome by using human genome information, the human genome information including information on a group of SNPs, the genotypes of the SNPs being identified in multiple individuals, in which method a sum of mutual informations between tag SNP candidates and target SNPs is used as an index for selecting the tag SNPs, and a computer system based on the principle, a computer program, and a DNA microarray on which nucleic probes corresponding to the tag SNPs selected by the means, and a production method thereof.
机译:本发明提供了标记SNP的选择方法,用于构成与标记SNP相对应的一组核酸探针,该标记SNP用于通过使用人类基因组信息,对人类基因组的SNP进行信息的插入。包括有关一组SNP的信息,在多个个体中识别出的SNP的基因型,在该方法中,将标记SNP候选物与目标SNP之间的互信息之和用作选择标记SNP的指标,并且基于计算机原理上,计算机程序和DNA微阵列及其生产方法,在其上与通过该方法选择的标签SNP相对应的核酸探针。

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