首页>
外国专利>
SYSTEMS AND METHODS FOR STUDYING INFLAMMATION-DRUG INTERACTIONS
SYSTEMS AND METHODS FOR STUDYING INFLAMMATION-DRUG INTERACTIONS
展开▼
机译:研究炎症-药物相互作用的系统和方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present disclosure provides compositions, systems, and tools for modeling liver inflammation and methods of using the same. The disclosure provides micropatterned hepatocyte-Kupffer cell co-cultures or Kupffer cell-treated hepatocyte co-cultures where hepatocytes maintain Kupffer cell-initiated activities during long-term culture. The in vitro liver inflammation models of the present disclosure may be useful for evaluating both acute as well as chronic inflammation-mediated toxicities of compounds in a pre-clinical setting.
展开▼