IONIZATION SOURCE FOR ELECTROSPRAY IONIZATION MASS SPECTROMETRY AND MS ANALYSIS

摘要

An ionization source for Electrospray Ionization (ESI) mass spectrometry includes a mass spectrometer having a source vacuum chamber having an inlet and an outlet. The outlet is disposed at an opening of the mass spectrometer. The ionization source further includes a hollow emission needle having an exit disposed at the inlet of the vacuum chamber. The hollow emission needle is configured to convey a first material toward the exit. An auxiliary line is disposed adjacent to the hollow emission needle to convey a second material toward the exit. A voltage supply apparatus is applied between the hollow emission needle and the mass spectrometer to establish a voltage between the hollow emission needle and the mass spectrometer and to induce particles to enter the mass spectrometer for analysis.