Tetradentate organic ligand H₃-MN-16Bn containing long alkyl group, precursor thereof, and method for preparing the same

摘要

A tetradentate organic ligand H₃-MN-16Bn containing a long alkyl group, a precursor thereof, and a method for preparing the same are revealed. A precursor of H₃-MN-16Bn, benzyl 16-bromohexadecanate, is obtained by esterification reaction of 16-bromohexadecanoic acid. Then bimolecular nucleophilic substitution reaction (S_N2) of Benzyl 16-bromohexadecanate with nitrogen sulfide (N₂S₂) is carried out to get H₃-MN-16Bn that is used as a standard hydrolysis metabolites of non-radioactive ¹⁸⁵Re-complex compound.