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Enzyme treatment apparatus for proteins using a hollow fiber membrane, and on-line proteomics method using same
Enzyme treatment apparatus for proteins using a hollow fiber membrane, and on-line proteomics method using same
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机译:使用中空纤维膜的蛋白质的酶处理装置以及使用该酶处理装置的在线蛋白质组学方法
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摘要
Provided are an enzyme treatment apparatus for proteins using a hollow fiber membrane and an on-line proteomics method using same. The enzyme treatment apparatus for proteins according to the present invention can increase a recovery rate of peptides, which are recovered through an enzyme treatment process, by basically solving the problem of low reproducibility of an enzyme activity which may occur during a conventional enzyme treatment process, and can also reduce a time for purification and provide higher yield by performing separation and purification through a single step. In particular, the present invention can be usefully applied for developing a disease-specific protein biomarker through a statistical analysis method having highly efficient detectability for proteins in research for finding biomarkers related to human diseases.
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