Combinations of peptides and peptides for use in Immunotherapy and methods to create holders for use Against Cancer and other cancers of the pancreas

摘要

The present Invention relates to Peptides, Proteins, Nucleic acids and Cells for use in immunotherapeutic methods. In particular, This refers to Immunotherapy against cancer.This also refers to epitope Peptide for tumor Associated T cells alone or in combination with other tumor Associated Peptides, for example, can be used as active ingredients in Pharmaceutical compositions intended to stimulate responses inmunita vaccine Rias or stimulate antitumor T cells after ex vivo will be transferred to the patients.The peptides bound to Molecules of the major histocompatibility complex (MHC), or peptides as such, may also be targets of Antibodies, T Lymphocyte receptor soluble Molecules, and other union.Claim 1: Peptide comprising an Amino Acid Sequence selected from the group consisting of SEQ ID no. 1 to the SEQ ID no. 161Sequences and variants thereof that are at least a 88% homologous to the SEQ ID no. 1 to the SEQ ID no. 161; in this variant binds to one or more Molecules of the major histocompatibility complex (MHC) and / or induces t-cell Cross reaction with the Peptide Variant; And a pharmaceutically acceptable Salt thereof, in which the Peptide is a polypeptide.