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fusion protein, engineered cell to express fusion protein, vector, and method for treating a cancer patient
fusion protein, engineered cell to express fusion protein, vector, and method for treating a cancer patient
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机译:融合蛋白,表达融合蛋白的工程细胞,载体和治疗癌症患者的方法
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摘要
The present invention relates generally to a fusion protein that when displayed on a cell can convert a negative signal into a positive signal in the cell. The fusion protein is a chimeric protein in that the protein comprises at least two domains, wherein the first domain is a polypeptide that is associated with a negative signal and the second domain is a polypeptide that is associated with a positive signal. Thus, the invention encompasses switch receptors that are able to switch negative signals to positive signals for enhancement of an immune response.
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