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Method for predicting clinical benefit in the treatment of neurodesenvolvimento neurological or neuropsychiatric disorders.

机译:预测治疗神经退行性神经症或神经精神疾病的临床益处的方法。

摘要

Abstract invention patent: "method to predict clinical benefit in the treatment of disorders of neurodesenvolvimento, neurological or neuropsychiatric.The invention relates to a method of in vitro provide an answer for patients with neurological or neuropsychiatric disorders, neurodesenvolvimento, is treated with a compound that has targeted the use glutamatu00e9rgica, comprising the steps of: I) to determine the concentration of prote u00edna of one, two, three, four.Five or six members of the family of factors of complement h or a mixture or a combination thereof, in a sample of a patient, (II) to compare the concentration of protein determined in step (I) with a value representative of the concentration of protein A, two, three, four, five... Or six members of the family of factors working h in patients with disorders of neurodesenvolvimento,Neurological or neuropsychiatric, (III), in which a greater concentration of protein with one, two, three, four, five or six members of the family of factors working in the sample of the patient who presents h neurodesenvolvimento disorders, neurological or neuropsychiatric is indicat Vat of a patient who will obtain clinical benefit of this treatment.And (IV) selecting this treatment to patients with disorders of neurodesenvolvimento, neurological or neuropsychiatric.
机译:抽象的发明专利:“预测神经脱皮病,神经性或神经精神疾病的临床疗效的方法。本发明涉及一种为患有神经性或神经精神性疾病的患者,用化合物治疗的体外方法。针对使用谷氨酸的用途,其包括以下步骤:I)确定补体h因子家族五种或六种成员或混合物或a的蛋白质的浓度。 (II)在患者样本中将其组合用于比较步骤(I)中确定的蛋白质浓度与代表蛋白质A,2、3、4、5 ...或6个成员的蛋白质浓度的值神经退行性神经病,神经病学或神经精神病学障碍患者中起作用的因素家族(III),其中较高浓度的蛋白质具有1、2、3、4、5或6个成员表现出神经退行性疾病,神经系统或神经精神疾病的患者样本中起作用的一系列因素表示将获得该治疗临床益处的患者的增值税。(IV)对患有神经退行性,神经系统疾病或神经系统疾病的患者选择该治疗方法神经精神病学。

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