prophylactic and / or therapeutic agent for mild cognitive impairment; and interstitial flow enhancing agent

摘要

prophylactic and / or therapeutic agent for mild cognitive impairment; and interstitial flow enhancing agent is provided a prophylactic and / or therapeutic drug for mild cognitive impairment, which can improve interstitial flow in the cerebral blood vessel and the like to achieve sufficient release of accumulated harmful proteins in the brain. prophylactic and / or therapeutic drug includes 6- [4- (1-cyclohexyl-1h-tetrazol-5-yl) butoxy] 3,4-dihydrocarbostyril or a salt thereof as an active ingredient. The prophylactic and / or therapeutic drug can improve an interstitial fluid flow around the blood vessels in a drainage passage to excrete the harmful proteins. the prophylactic and / or therapeutic drug for mild cognitive impairment may take the form of an oral administration pharmaceutical, a liquid oral administration pharmaceutical, or an injectable preparation. The prophylactic and / or therapeutic drug for mild cognitive impairment may be used for the prevention and / or treatment of cerebral amyloid angiopathy, and may further be used for amelioration of lewy body disease, down syndrome, or muscle degeneration.