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System for magnetic vectorization of radiopharmaceutical for the relief of pain caused by bone disease.

机译:用于减轻骨骼疾病引起的疼痛的放射性药物磁性矢量化系统。

摘要

Summary summary of invention patent for "system for magnetic vectorization of radiopharmaceutical for the relief of pain caused by bone disease" aims to patent the invention to the vectorization of the radiopharmaceutical connected to a magnetic polymer or biological material, C Om affinity for any structure present in the micro environment of a bone metastasis.Or a bone disease of any kind, the example of 153Sm EDTMP -, and system of magnetic particles, for use in the treatment of pain caused by bone disease. The system will be composed of biocompatible magnetic particles for intravenous application, in the vicinity of the bone lesion.This invention patent is carried of the radiopharmaceutical to bone tissue injury, through the action of the magnetic particles modulated by an external magnetic field, to destroy the nerve endings and eliminate pain.The external magnet causes the particles to be retained for as long as possible in the vicinity of the bone lesion, so that the biological material or polymer with affinity for any structure of the microenvironment of bone metastases, or bone disease of any kind, call if any A structure of the microenvironment of bone disease.The association of vectorization magnetic polymer or biological material permits high concentration and setting the quantity of radiopharmaceutical administered in the region around the bone tissue injury, implying, in reducing the side effects associated with the biodistribution.
机译:“用于减轻由骨疾病引起的疼痛的放射性药物的磁性矢量化系统”的发明专利摘要旨在将本发明授予与磁性聚合物或生物材料连接的放射性药物的矢量化的专利,对于任何形式的C om亲和力153 Sm EDTMP-或任何类型的骨骼疾病,以及磁性颗粒系统,用于治疗骨骼疾病引起的疼痛。该系统将由生物相容性磁性颗粒组成,用于在骨病变附近静脉内应用。本发明专利是放射性药物对骨组织的伤害,它通过外部磁场调制的磁性颗粒的作用来破坏神经末梢消除疼痛。外部磁体使颗粒在骨病变处尽可能长的保留,从而使生物材料或聚合物对骨转移或骨微环境的任何结构都具有亲和力任何类型的疾病,如果有的话,则称其为骨疾病微环境的A结构。矢量化磁性聚合物或生物材料的结合允许高浓度并设定在骨组织损伤周围区域施用的放射性药物的量,这意味着减少了与生物分布有关的副作用。

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