vaginal ring for dispensing a water soluble polymer, and method for manufacturing a vaginal ring for dispensing a water soluble polymer

摘要

1/1 overview “vaginal ring for dispensing a water-soluble polymer, and method for making a vaginal ring for dispensing a water-soluble polymer” Compositions for inhibiting transmission of a sexually transmitted infection containing one or more polyanionic microbicides, such as carrageenan, including lambda carrageenan, as well as water-soluble metal salts and antiretroviral agents, are described. specified comprising nnrtis and nrtis. Also described are methods for making and using the compositions. Intravaginal rings for dispensing water-soluble compounds, and preferably water-soluble polymers of high molecular weight at essentially zero order velocity, are also described. the rings include an outer layer of non-water swellable elastomer, and preferably high molecular weight water-soluble polymer and an inner layer of water-soluble polymer, which is embedded in the outer layer, and an orifice through the outer layer for release thereof only through this orifice.