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TRUNCATED L1 PROTEIN OF HUMANT PAPILLOMAVIRUS TYPE 33

机译:截短的人乳头瘤病毒33型L1蛋白

摘要

The present invention relates to a truncated L1 protein of Human Papillomavirus (HPV) Type 33, a sequence encoding the same, a method for preparing the same, and a virus-like particle comprising the same, wherein the protein and the virus-like particle are useful for preventing HPV (particularly HPV33) infection, and a disease caused by HPV (particularly HPV33) infection, such as cervical cancer. The invention also relates to the use of the protein and the virus-like particle in the preparation of a pharmaceutical composition or a vaccine for preventing HPV (particularly HPV33) infection, and a disease caused by HPV (particularly HPV33) infection, such as cervical cancer.
机译:本发明涉及33型人乳头瘤病毒(HPV)的截短的L1蛋白,编码该L1蛋白的序列,其制备方法以及包含该蛋白的病毒样颗粒,其中该蛋白和病毒样颗粒可用于预防HPV(尤其是HPV33)感染以及由HPV(特别是HPV33)感染引起的疾病,例如宫颈癌。本发明还涉及蛋白质和病毒样颗粒在制备用于预防HPV(特别是HPV33)感染和由HPV(特别是HPV33)感染引起的疾病例如宫颈的药物组合物或疫苗中的用途。癌症。

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