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USE OF AN INFLUENZA VIRUS AND AN OIL-IN-WATER EMULSION ADJUVANT TO INDUCE CD4 T-CELL AND/OR IMPROVED B-MEMORY CELL RESPONSE
USE OF AN INFLUENZA VIRUS AND AN OIL-IN-WATER EMULSION ADJUVANT TO INDUCE CD4 T-CELL AND/OR IMPROVED B-MEMORY CELL RESPONSE
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机译:使用流感病毒和水包油乳状液佐剂诱导CD4 T细胞和/或改善的B记忆细胞反应
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摘要
The present invention relates to influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to multivalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from at least two influenza virus strains, at least one strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant.
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