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Concentration of iron in blood and changes within HFE gene as risk factors for cancers in men

机译:血液中铁的浓度和HFE基因内的变化是男性癌症的危险因素

摘要

in the notification, it was found that there is a correlation between genotype hfe gene (rs 1799945), iron concentration in serum and the risk of cancers in men. the object of the application is how to determine the risk of cancer.this method is characterized by the fact that includes assessment of the constitutional changes in gene hfe his63asp (rs 1799945) and assessment of iron levels in biological sample test man, with the combination of individual genotypes with certain level of iron shows significantly zwiu0119kszo ne or reduced risk of developing cancers and considered,the risk of cancers in men: - for hfe cc genotype at the concentration of iron in serum 750 mcg / l (or concentration in any biological material corresponding to the concentration in the serum) is increased; - for genotype hfe cc at the concentration of iron in serum 1450 - 1900 mcg / l (or concentration any biological material corresponding to the concentration in the serum) is reduced.
机译:在该通知中,发现基因型hfe基因(rs 1799945),血清中的铁浓度和男性患癌症的风险之间存在相关性。本申请的目的是确定癌症的风险。此方法的特点是结合使用结合了对hfe his63asp(rs 1799945)基因的组成变化进行评估,以及对生物样本测试人员中的铁水平进行评估。某些含铁水平的个体基因型显着降低或罹患癌症的风险,并且考虑到男性患癌症的风险:-对于hfe cc基因型,血清铁浓度<750 mcg / l(或与血清中浓度相对应的任何生物材料中的浓度增加; -对于基因型hfe cc,血清中铁的浓度1450-1900 mcg / l(或对应于血清中任何生物物质的浓度)降低。

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