首页> 外国专利> In vitro method and kit for the prognosis or prediction of response to treatment with antipsychotic agents by patients who have suffered a first psychotic episode (Machine-translation by Google Translate, not legally binding)

In vitro method and kit for the prognosis or prediction of response to treatment with antipsychotic agents by patients who have suffered a first psychotic episode (Machine-translation by Google Translate, not legally binding)

机译:用于首次精神病发作的患者预后或预测抗精神病药物治疗反应的体外方法和试剂盒(由Google Translate进行机器翻译,不具有法律约束力)

摘要

In vitro method and kit for the prognosis or prediction of the response to treatment with antipsychotic agents by patients who have suffered a first psychotic episode. The present invention refers to an in vitro method of predicting or predicting the response to treatment with antipsychotic drugs, by subjects who have suffered a first psychotic episode (fep), and in particular, the use of expression value, in an isolated biological sample of said subjects, of the ratio formed by two of the isoforms - active and truncated isoform - of the receptor (trkb) of the neuronal growth factor bdnf, called trkb-fl and trkb-t, respectively. The present invention further discloses kits and uses thereof for carrying out the method of the invention. (Machine-translation by Google Translate, not legally binding)
机译:体外方法和试剂盒,用于预后或预测患有第一次精神病发作的患者对抗精神病药治疗的反应。本发明涉及一种体外方法,该方法通过在第一次分离的生物学样品中遭受第一次精神病发作(fep),特别是使用表达值的受试者来预测或预测对抗精神病药治疗的反应。所述受试者的神经元生长因子bdnf受体(trkb)的两个同工型(活性和截短同工型)形成的比率分别称为trkb-fl和trkb-t。本发明进一步公开了试剂盒及其用于实施本发明方法的用途。 (通过Google翻译进行机器翻译,没有法律约束力)

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