NOVEL FLUORESCENT BORON-SUBSTITUTED DIPYRROMETHENES AND USE THEREOF FOR DIAGNOSIS

摘要

The present invention relates to novel fluorescent compounds derived from nonfluorinated dipyrromethene boron, process for their preparation and their use for fluorescent labeling of biological molecules. The invention further relates to biological molecules labeled with said fluorescent compounds and their use in detection methods such as medical diagnostic methods; in particular, the detection methods according to the invention are particularly useful for the diagnosis of neurodegenerative diseases such as Alzheimer's disease.