BIOENZYMATIC SYNTHESIS OF TETRAHYDROCANNABIVARIN (THC-V), CANNABINOL (CBN), AND CANNABIVARIN (CBV) AND THEIR USE AS THERAPEUTIC AGENTS

摘要

A method for the bio-enzymatic synthesis of tetrahydrocannabivarin (THC-v), cannabivarin (CBV) and cannabinol (CBN) by contacting a compound according to Formula I with a cannabinoid synthase enzyme. The cannabinoids are produced in the presence of a solvent in a bioreactor equipped with a controller.