METHOD FOR IDENTIFYING BY MASS SPECTROMETRY AN UNKNOWN MICROORGANISM SUBGROUP FROM A SET OF REFERENCE SUBGROUPS

摘要

Method for identifying by mass spectrometry an unknown microorganism subgroup from among a set of reference subgroups, comprising a step of constructing a knowledgebase and a model allowing classification by associated subgroup, which step is carried out on the basis of at least one acquired set of training spectra taken from microorganisms identified as belonging to subgroups of a group, said step comprising: constructing an adjusting model allowing shifts in mass-to-charge ratio of the acquired spectra to be corrected on the basis of reference mass-to-charge ratios common to the various subgroups; adjusting the mass-to-charge ratios of all of the lists of peaks of the training spectra; and constructing a model allowing classification by subgroup and the associated knowledgebase on the basis of the adjusted training spectra.