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Tetra-specific, octameric binding agents and antibodies against Clostridium difficile toxin A and toxin B for treatment of C. difficile infection

机译：四特异性八聚体结合剂和抗艰难梭菌毒素A和毒素B的抗体，用于治疗艰难梭菌感染

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摘要

Novel, antibody-based binding agents derived from human and camelid immunoglobulins are described. These binding agents recognize and bind with specificity to

机译：描述了衍生自人和骆驼科动物免疫球蛋白的新型基于抗体的结合剂。这些结合剂识别并特异性结合

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公开/公告号AU2016215087A1

专利类型
公开/公告日2017-08-17

原文格式PDF
申请/专利权人 UNIVERSITY OF MARYLAND BALTIMORE;
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申请/专利号AU20160215087
发明设计人 FENG HANPING;GUAN YONGJUN;ZHANG YONGRONG;YANG ZHIYONG;SHI LIANFA;
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申请日2016-02-05
分类号C07K16/12;A61K39/395;A61K39/40;A61P31/04;
国家 AU
入库时间 2022-08-21 13:32:28

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8. High prevalence of subclass-specific binding and neutralizing antibodies against clostridium difficile toxins in adult cystic fibrosis sera:Possible mode of immunoprotection against symptomatic c. difficile infection [O] . Monaghan, Tanya M., Negm, Ola H., Mackenzie, Brendon, 2017

9. Hybridoma Cell Lines amd Monoclonal Antibodies to Clostridium difficile Toxins A and B. [R] . Rothman, S., Gentry, M. K. 1986

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