TREATMENT OF ALZHEIMER'S DISEASE LOSS OF COGNITION MEMORY LOSS AND DEMENTIA WITH SEX STEROID PRECURSORS IN COMBINATION WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS

摘要

In a sensitive warm-blooded animal, it reduces the risk of developing breast cancer, uterine cancer or endometrial cancer while alleviating or eliminating the occurrence of facial flushing, vasomotor symptoms and hyperemia, and also reduces osteoporosis, hypercholesterolemia, hyperlipidemia, atherosclerosis, As a novel method having an advantageous effect by inhibiting development of insulin resistance, type 2 diabetes, muscle mass loss, obesity, Alzheimer's disease, cognitive loss, amnesia or vaginal dryness, sex steroid precursors, especially dihydroepiandrosterone ) And an anti-estrogen or selective estrogen receptor modulator, especially a compound having the general formula: Pharmaceutical compositions and useful kit (s) for delivery of the active ingredient (s) are also disclosed by the present invention.