CXCR2 Method for Inducing Endodermal and Mesodermal Differentiation from Human Pluripotent Stem Cells by CXCR2 Suppression

摘要

The present invention relates to a method of differentiating endoderm and mesodermal differentiation of human pre-differentiating stem cells through CXCR2 inhibition, and more particularly to a method of inhibiting the expression of surface receptor CXCR2 of human pre-differentiation stem cells by shRNA technique, Lt; / RTI The endoderm and mesenchymal differentiation of human pre-differentiating stem cells through inhibition of CXCR2 according to the present invention promotes the differentiation into specific goblet cells, which is the first important step for inducing differentiation into specific cells, As a therapeutic agent, the efficiency and usefulness of stem cells can be enhanced.