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12-A-7-IMIDAZO12-APYRIDIN-7-AMINES AS IMAGING TOOLS
12-A-7-IMIDAZO12-APYRIDIN-7-AMINES AS IMAGING TOOLS
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机译:[12-A] -7-咪唑并[12-A]吡啶-7-氨基作为成像工具
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摘要
The present invention relates to compounds of formula (I), or pharmaceutically acceptable acid addition salts thereof. The compounds may be used to combine and image tau aggregates and related beta-sheet aggregates, such as other beta-amyloid aggregates or alpha-synuclein aggregates: (I) In this formula, R 1 is lower alkyl or lower alkyl substituted by halogen; R 2 and R 3 are hydrogen or tritium.
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机译:本发明涉及式(I)的化合物或其药学上可接受的酸加成盐。这些化合物可用于合并tau聚集体和相关的β-折叠聚集体(例如其他β-淀粉样聚集体或α-突触核蛋白聚集体)并对其进行成像:(I)在该公式中,R Sup> 1 Sup为低级烷基或被卤素取代的低级烷基; R 2 Sup>和R 3 Sup>是氢或tri。
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