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PHARMACEUTICAL COMPOSITIONS COMPRISING IMMUNOLOGICAL FORMULATIONS FOR TREATING CEREBRAL INFARCTION

机译:包含用于治疗脑梗死的免疫制剂的药物组合物

摘要

PROBLEM TO BE SOLVED: To provide pharmaceutical compositions for treating cerebral infarction administrable to patients in a post-acute stage of cerebral infarction.;SOLUTION: The invention provides a pharmaceutical composition for treating cerebral infarction, comprising a thrombolytic agent and an inhibitor that inhibits the binding of a vascular endothelial growth factor (VEGF) to a receptor thereof. The pharmaceutical composition of the invention for treating cerebral infarction may be administered to a patient after a post-acute stage of cerebral infarction. The pharmaceutical composition of the invention for treating cerebral infarction may contain a tissue type plasminogen activator (t-PA) or a derivative thereof. The pharmaceutical composition of the invention for treating cerebral infarction may contain an anti-VEGF-A neutralizing antibody or a derivative thereof.;SELECTED DRAWING: None;COPYRIGHT: (C)2019,JPO&INPIT
机译:解决的问题:提供治疗脑梗塞的急性期后的患者可服用的治疗脑梗塞的药物组合物。血管内皮生长因子(VEGF)与其受体的结合。用于治疗脑梗塞的本发明的药物组合物可以在脑梗塞的急性期后给予患者。用于治疗脑梗塞的本发明的药物组合物可以包含组织型纤溶酶原激活剂(t-PA)或其衍生物。用于治疗脑梗塞的本发明的药物组合物可以包含抗VEGF-A中和抗体或其衍生物。;选择制图:无;版权:(C)2019,JPO&INPIT

著录项

  • 公开/公告号JP2018158948A

    专利类型

  • 公开/公告日2018-10-11

    原文格式PDF

  • 申请/专利权人 NIIGATA UNIV;

    申请/专利号JP20180132193

  • 发明设计人 SHIMOHATA KIYOSHI;

    申请日2018-07-12

  • 分类号A61K38/49;A61P9/10;A61K39/395;A61P43/00;A61P7/02;

  • 国家 JP

  • 入库时间 2022-08-21 13:14:34

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