LABELING METHOD FOR TARGET GENE, VECTOR SYSTEM, CELL, AND KITS FOR EDITING TARGET GENE MAINTAINING GENE ACTIVITY

摘要

PROBLEM TO BE SOLVED: To provide methods for labeling a target gene, vector systems, cells, and kits for editing a target gene maintaining gene activity.;SOLUTION: Provided is a labeling method for a target gene capable of confirming gene activity, the labeling method comprising replacing a gene encoding a fusion protein of a target protein encoded by the target gene and a labeling protein with the target gene by homologous recombination, the fusion protein being characterized by comprising a linker having a cleavage sequence of an endogenous enzyme, between the target protein and the labeling protein.;SELECTED DRAWING: Figure 1;COPYRIGHT: (C)2018,JPO&INPIT