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ASYMMETRICAL REVERSIBLE NEUROMUSCULAR BLOCKING SUBSTANCE WITH SUPER SHORT, SHORT OR MIDDLE DURATION TIME
ASYMMETRICAL REVERSIBLE NEUROMUSCULAR BLOCKING SUBSTANCE WITH SUPER SHORT, SHORT OR MIDDLE DURATION TIME
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机译:具有超短,短或中等持续时间的非对称可逆神经肌肉阻滞物质
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摘要
PROBLEM TO BE SOLVED: To provide a neuromuscular blocking compound.;SOLUTION: A pharmaceutical composition contains a biocompatible solvent and a compound represented by formula (I). In the pharmaceutical composition, the biocompatible solvent contains a compound which contains 0.9% saline water, has a pH of approximately 2.5 to 3.5, has a concentration of approximately 1-10 mg/ml and is represented by formula (I). A kit contains the pharmaceutical composition in a first container and a thiol compound in a second container. A method includes reacting alcohol having a right edge or a left edge of formula (I) with a maleic anhydride or dichlorosuccinic anhydride, and reacting the obtained reaction product with alcohol on the other end to produce the compound represented by formula (I).;SELECTED DRAWING: Figure 4;COPYRIGHT: (C)2018,JPO&INPIT
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