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Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene

机译:使用膀胱癌特异性甲基化标记基因的膀胱癌诊断试剂盒和芯片

摘要

The present invention relates to a kit and nucleic acid chip for diagnosing bladder cancer using a bladder cancer-specific marker gene. More particularly, the invention relates to a kit and nucleic acid chip for diagnosing bladder cancer, which can detect the promoter methylation of a bladder cancer-specific gene, the promoter or exon region of which is methylated specifically in transformed cells of bladder cancer. The use of the diagnostic kit or nucleic acid chip of the invention enables diagnosis of bladder cancer at an early stage of transformation, thus enabling early diagnosis of bladder cancer, and can diagnose bladder cancer in a more accurate and rapid manner compared to a conventional method.
机译:本发明涉及用于使用膀胱癌特异性标记基因诊断膀胱癌的试剂盒和核酸芯片。更具体地,本发明涉及用于诊断膀胱癌的试剂盒和核酸芯片,其可以检测膀胱癌特异性基因的启动子甲基化,该基因的启动子或外显子区域在膀胱癌的转化细胞中被特异性甲基化。与常规方法相比,使用本发明的诊断试剂盒或核酸芯片能够在转化的早期阶段诊断膀胱癌,从而能够早期诊断膀胱癌,并且能够以更准确和快速的方式诊断膀胱癌。 。

著录项

  • 公开/公告号US10113203B2

    专利类型

  • 公开/公告日2018-10-30

    原文格式PDF

  • 申请/专利权人 GENOMICTREE INC.;

    申请/专利号US201715709348

  • 发明设计人 TAE JEONG OH;SUNG WHAN AN;YOUNG HO MOON;

    申请日2017-09-19

  • 分类号C12Q1/68;C12Q1/6886;C12Q1/686;

  • 国家 US

  • 入库时间 2022-08-21 13:05:30

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