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Composition to induce bone marrow stem cell mobilization

机译:诱导骨髓干细胞动员的成分

摘要

A pharmaceutical composition to induce bone marrow stem cell mobilization from the bone marrow to peripheral blood in patients suffering from pathological conditions, such as diabetes, or subjected to treatments that impair cell mobilization, or in patients suffering from the so called “poor mobilizer” condition, includes at least one therapeutic agent that inhibits production and/or action of the human cytokine oncostatin M (OSM), a macrophage derived factor, that prevents mobilization of stem cells.
机译:一种药物组合物,用于在患有病理性疾病(例如糖尿病)的患者中或在进行了损害细胞动员的治疗的患者中或在所谓的“不良动员”条件下诱导从骨髓向外周血动员骨髓干细胞包括至少一种抑制人细胞因子癌抑素M(OSM)的产生和/或作用的治疗剂,OSM是一种巨噬细胞衍生因子,可防止干细胞动员。

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