首页> 外国专利> APPLICATIONS FOR ESTRADIOL IN PREPARING ANTI-SMALL CELL LUNG CANCER AND/OR OVARIAN CANCER AND/OR OSTEOSARCOMA PRODUCTS

APPLICATIONS FOR ESTRADIOL IN PREPARING ANTI-SMALL CELL LUNG CANCER AND/OR OVARIAN CANCER AND/OR OSTEOSARCOMA PRODUCTS

机译:雌二醇在制备抗小细胞肺癌和/或卵巢癌和/或骨肉瘤产品中的应用

摘要

This invention discloses uses for estradiol in preparing anti-small cell lung cancer and/or ovarian cancer and/or osteosarcoma products. This invention provides uses for estradiol in preparing anti-small cell lung cancer and/or ovarian cancer and/or osteosarcoma products. From carrying out cancer drug repositioning for the FDA- and CFDA-approved drug estradiol, experiments for this invention show, based on screening of non-anti-cancer drugs for various cancer cell lines (tissue types) and mutation sites, that estradiol has a new use as an anti-small cell lung cancer and/or ovarian cancer and/or osteosarcoma medication, thus achieving a new purpose for an old drug.
机译:本发明公开了雌二醇在制备抗小细胞肺癌和/或卵巢癌和/或骨肉瘤产品中的用途。本发明提供了雌二醇在制备抗小细胞肺癌和/或卵巢癌和/或骨肉瘤产品中的用途。从针对FDA和CFDA批准的雌二醇进行癌症药物重新定位后,本发明的实验表明,基于针对多种癌细胞系(组织类型)和突变位点的非抗癌药物的筛选,雌二醇具有用作抗小细胞肺癌和/或卵巢癌和/或骨肉瘤的药物,从而达到了旧药物的新目的。

著录项

  • 公开/公告号US2018185386A1

    专利类型

  • 公开/公告日2018-07-05

    原文格式PDF

  • 申请/专利权人 SHANGHAI JIAO TONG UNIVERSITY;

    申请/专利号US201515740766

  • 发明设计人 YONGYONG SHI;ZHIJIAN SONG;

    申请日2015-06-30

  • 分类号A61K31/565;A61P35;

  • 国家 US

  • 入库时间 2022-08-21 12:57:54

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