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Method and kit for determining the probability that a patient will develop a severe case of dengue

机译:确定患者患上严重登革热病例的可能性的方法和试剂盒

摘要

A method for determining, in vitro, the probability of a patient developing severe dengue, based on a blood sample, according to a) the quantity in the blood sample of at least one marker, which is olfactomedin 4, is determined, b) the quantity of olfactomedin 4 determined in step a) is compared with a reference quantity of the marker obtained from a group of individuals who have been diagnosed with non-severe dengue, wherein, if the quantity of olfactomedin 4 determined in step a) is greater than the reference quantity established in step b), it is determined that the patient will develop severe dengue.
机译:一种根据血样在体外确定患者罹患严重登革热的可能性的方法,其依据是:a)确定血样中至少一种标记物,即嗅觉素4的量,b)将步骤a)中确定的olfactomedin 4的量与从一组已诊断为非严重登革热的个体中获得的标记物的参考量进行比较,其中,如果步骤a)中确定的olfactomedin 4的量大于根据步骤b)中确定的参考量,确定患者将患上严重的登革热。

著录项

  • 公开/公告号US9933426B2

    专利类型

  • 公开/公告日2018-04-03

    原文格式PDF

  • 申请/专利权人 BIOMERIEUX;

    申请/专利号US201515117977

  • 发明设计人 FRÉDÉRIC BEDIN;ROMAIN FRAGNOUD;

    申请日2015-02-12

  • 分类号A61K39/395;C07K16/18;C07K16/28;A61K39;C07K16/44;G01N33/569;

  • 国家 US

  • 入库时间 2022-08-21 12:55:38

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