1. Characteristic 1: multifunctional immune components, including 13 different dosa protein mixtures, plus a physiologically acceptable vehicle, Each of them contains a kind of vesicular polygonal polymer with different serum types of single cell Streptococcus polymer, which combines a carrier protein and vesicular polygonal polymer, and is prepared together with serum types 1, 3, 4, 5, 6a, 6F, 7F, 9V, 14, 18C, 19A, 19F and 23F, wherein the transport protein is crm8321; 83298327y, wherein the polymer is polymer; By reducing ammonia. Requirement 3: immune ingredients meeting requirement 2,Adyuvante is an aluminum adyuvante. Requirement 6: the immune composition determined according to any one of 1-4 requirements characterized by vaccine application; requirement 8: the immune composition determined according to any one of 1-4 requirements for infant and young child vaccination, The vaccination plan is at 2,4,6 and 12-15 months old Requirement 9: immune composition that meets any one of the 1-4 requirements for vaccination of juveniles and adults. 1. Claim 10: a syringe made of 1, 3, 4, 5, 6a, 6b, 7F, 9V, 14, 18C, 19A, 19F and 23F single dose of polycystal Spirulina fluid which is incorporated into crm8321;where each 0.5 ml dose is formulated to contain 2.2 mg of each saccharide, except 6B which is 4 mg, approximately 29 mg of the CRM₁₉₇ carrier protein,0.125 mg of elemental aluminum adjuvant (0.5 mg of aluminum phosphate) and buffer of sodium chloride and sodium succinate as excipients. Claim 13: A process for preparing a multivalent immunogenic composition, comprising 13 different polysaccharide-protein conjugates, together with a physiologically acceptable vehicle, where each of the conjugates comprises a different capsular polysaccharide conjugated to a CMR₁₉₇ carrier protein,The polyurethanes were prepared from the serum of pneomone streptock 1, 3, 4, 5, 6a, 6b, 7F, 9V, 14, 18C, 19A, 19F and 23F. The single polyurethanes were purified by centrifugation, precipitation, exudation and chromatography; 2. Purified polymerases are chemically active to produce anesthetics that can react with cmr83218329 protein;once activated, each capsular polysaccharide is individually conjugated to the CRM₁₉₇ transporter protein to form a glycoconjugate; the individual glycoconjugates are purified and compounded to formulate the immunogenic composition.
展开▼
