Formulation containing solid lipid nanoparticles and use of the same Flavonoide

摘要

Formulation containing solid lipid nanoparticles Flavonoide and use thereof the present invention relates to a formulation containing solid lipid nanoparticle of F lavonoide rutin.In the concentration range of 0.05 to 18.0%, including: natural lipids, emulsif icantes, promoting agent for absorption and active.The components of the topical formulation, in addition to the NLSS of rutin, include emulsifiers (1-7%), emollients (1 - 7%), moisturizers (0.5 - 3.0%), preservative (0.1 and 3.5%) and vehicle (60 90%).The formulation developed has potential antioxidant, reducing the ageing of the skin due to the rutin and photoprotection physics, due to the skin barrier is being promoted by the NLS.This promotes an increase of skin penetration of rutin and increase its stability.Enhances its properties in skin providing a greater penetration in the deeper layers of the skin and increase the capacity of the Flavonoide photo protective due to the synergistic effect of absoRu00e7u00e3o of UV radiation by routine associated with the reflection and scattering of radiation by particles of nanometer size.