首页> 外国专利> Use of propylene glycol as solvent and the excipient QSP for single drug formulation with active principles with molar mass less than 500 and is soluble in propylene glycol and specifyThe use of active principles, isotretinoin, diclofenac potassium, sodium citrate, tamoxifen, exemestane, finasteride, estradiol.Dydrogesterone and estriol in the specific composition of seven medicinal patches using propylene glycol as solvent and the excipient QSP

Use of propylene glycol as solvent and the excipient QSP for single drug formulation with active principles with molar mass less than 500 and is soluble in propylene glycol and specifyThe use of active principles, isotretinoin, diclofenac potassium, sodium citrate, tamoxifen, exemestane, finasteride, estradiol.Dydrogesterone and estriol in the specific composition of seven medicinal patches using propylene glycol as solvent and the excipient QSP

机译:丙二醇作为溶剂和赋形剂QSP用于单一药物制剂,其活性成分的摩尔质量小于500,并且可溶于丙二醇,并规定了活性成分的使用:异维A酸,双氯芬酸钾,柠檬酸钠,他莫昔芬,依西美坦,非那雄胺,以丙二醇为溶剂和赋形剂QSP制成的七个药用贴剂的特定组成中的雌二醇,二氢孕酮和雌三醇

摘要

Use of propylene glycol as solvent and the excipient QSP for single drug formulation with active principles with molar mass less than 500 and is soluble in propylene glycol and specifyThe use of active principles, isotretinoin, diclofenac potassium, sodium citrate, tamoxifen, exemestane, finasteride, estradiol.Dydrogesterone and estriol in the specific composition of seven medicinal patches using propylene glycol as solvent and the excipient QSP.The field of application is the pharmaceutical industry to the area of transdermal drug formulations.The use of drugs isotretinoin (1), diclofenac potassium (2), (3), tamoxifen citrate.Citrate of tamoxifen and exemestane (4) finasteride (5) estradiol + dydrogesterone (6) estriol (7) for the production of seven transdermal formulation characterized by using propylene glycol as u00faniThe co solvent and the excipient QSP.As well as the use of propylene glycol as solvent and the excipient QSP for one single drug formulations for patches in compositions that use the propylene glycol as a solvent and.Xcipiente QSP in percentage of 80% to 100% of the QSP without the use of hydro spirit gels and creams. .
机译:丙二醇作为溶剂和赋形剂QSP用于单一药物制剂,其有效成分的摩尔质量小于500,并且可溶于丙二醇,并指定了有效成分的用途:异维甲酸,双氯芬酸钾,柠檬酸钠,他莫昔芬,依西美坦,非那雄胺,雌二醇,以丙二醇为溶剂和赋形剂QSP组成的七个药用贴片的特定成分中的地屈孕酮和雌三醇。应用领域是制药行业,用于经皮药物制剂领域。药物异维A酸(1),双氯芬酸钾的用途(2),(3),柠檬酸他莫昔芬。他莫昔芬和依西美坦的柠檬酸盐(4)非那雄胺(5)雌二醇+ dydrogesterone(6)雌三醇(7)用于生产七个以丙二醇为辅剂的透皮制剂以及使用丙二醇作为溶剂和赋形剂QSP用于一种单一药物制剂的复合制剂中的贴剂使用丙二醇作为溶剂和Xcipiente QSP的比例为QSP的80%至100%,而无需使用水性油凝胶和乳霜。 。

著录项

  • 公开/公告号BR102017027187A2

    专利类型

  • 公开/公告日2018-08-07

    原文格式PDF

  • 申请/专利权人 MARIO VIRGILIO DE CARVALHO JUNIOR;

    申请/专利号BR20171027187

  • 发明设计人 MARIO VIRGILIO CARVALHO JUNIOR;

    申请日2017-12-15

  • 分类号A61K31/565;A61K31/138;A61K31/196;A61K31/203;A61K31/5685;A61K31/58;A61K47/10;A61P5/24;A61P5/30;A61P17/10;A61P17/14;A61P29;A61P35;

  • 国家 BR

  • 入库时间 2022-08-21 12:53:55

相似文献

  • 专利
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号