SUBSTITUTED COMPOUNDS OF TETRAHYDROCHINOLINONE AS MODULATORS OF RHTINOID ORPHANE GAMMA RECEPTORS (RORγ)

摘要

The present invention relates to substituted tetrahydroquinolinone and related compounds of formula (I), which are therapeutically applicable as retinoid orphan receptor modulators (RORs), in particular, as RORγ modulators. These compounds are useful in the treatment and prevention of diseases and / or disorders, in particular diseases and / or disorders caused by the RORγ receptor. The present invention also provides for the preparation of compounds and dosage forms containing at least one substituted tetrahydroquinolinone or one related compound of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient for this.