Pharmaceutical composition for the prevention and treatment of diabetes or obesity comprising a compound that inhibits the activity of dipeptidyl peptidase-IV and other antidiabetic or anti-obesity agents as active ingredients

摘要

A pharmaceutical composition for use in the prevention and treatment of diabetes or obesity, comprising as active ingredients: (1) a compound represented by the following Formula 1, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof, and (2) one or more different antidiabetic or anti-obesity agents, wherein the other antidiabetic or anti-obesity agents are selected from the group consisting of biguanides, insulin sensitizers, insulin secretagogues, α-glucosidase inhibitors, and antagonists of the cannabinoid receptor 1. ** Formula ** (where, X is OR1, SR1, or NR1R2, wherein R1 and R2 are independently C1-C5 lower alkyl, or R1 and R2 of NR1R2 can form a 5- to 7-membered ring members containing a heteroelement of O)