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intrathecal or epidural administration of 3 - (1S, 2S) -3- (dimethylamino) -1-ethyl-2-methylpropyl phenol

机译:鞘内或硬膜外给药3-[(1S,2S)-3-(二甲基氨基)-1-乙基-2-甲基丙基]苯酚

摘要

3 - [(1S, 2S) -3- (dimethylamino) -1-ethyl-2-methylpropyl] phenol or a physiologically acceptable salt thereof for use in the treatment or local inhibition of pain, characterized in that an amount is administered therapeutically effective of a composition comprising 3 - [(1S, 2S) -3- (dimethylamino) -1-ethyl-2-methylpropyl] phenol or a physiologically acceptable salt thereof to a subject in need in a space that is essentially thrombocyte-free selected from the group consisting of the intrathecal, epidural and intracerebroventricular spaces, characterized in that - the administration of said composition does not result in any peripheral or supraspinally mediated side effects and - said subject is a human.
机译:3-[(1S,2S)-3-(二甲基氨基)-1-乙基-2-甲基丙基]苯酚或其生理上可接受的盐,用于治疗或局部抑制疼痛,其特征在于所述量的药物在治疗上有效包含3-[(1S,2S)-3-(二甲基氨基)-1-乙基-2-甲基丙基]苯酚或其生理学上可接受的盐的组合物在需要基本不含血小板的空间中的用途鞘内,硬膜外和脑室内空间组成的组,其特征在于-所述组合物的给药不会导致任何外周或脊髓上介导的副作用,并且-所述受试者是人类。

著录项

  • 公开/公告号ES2663403T3

    专利类型

  • 公开/公告日2018-04-12

    原文格式PDF

  • 申请/专利权人 GRÜNENTHAL GMBH;

    申请/专利号ES20120747973T

  • 申请日2012-07-27

  • 分类号A61K31/137;A61K9;A61K45/06;A61P25/04;

  • 国家 ES

  • 入库时间 2022-08-21 12:48:40

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