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Methods and compositions for the diagnosis and prognosis of renal injury and renal insufficiency

机译:诊断和预后肾损伤和肾功能不全的方法和组合物

摘要

A method for assessing renal status in a subject, comprising: determining a measured value for a concentration of TIMP2 in urine and a concentration of IGFBP7 in urine; determine a measured value for a urine production and optionally in addition to a serum creatinine concentration; combine, in a single value, the measured values obtained to provide a test resu and correlating the test result with the renal state of the subject, in which said correlation stage comprises correlating the test result (s) with one or more of diagnosis, risk stratification, prognosis, classification and monitoring of renal status. of the subject.
机译:一种评估受试者的肾脏状态的方法,包括:确定尿中TIMP2的浓度和尿中IGFBP7的浓度的测量值。确定尿液产生的测量值,以及测定血清肌酐浓度的方法;将获得的测量值合并为一个值,以提供测试结果;使测试结果与受试者的肾脏状态相关联,其中所述相关阶段包括使测试结果与肾脏状态的诊断,风险分层,预后,分类和监测中的一项或多项相关联。的主题。

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