HUMAN ENDOMETRIAL CANCER MARKER, ANTIBODY, AND APPLICATION OF ANTIBODY

摘要

A new human endometrial cancer tumor marker, named GAB31. The tumor marker is abnormally glycosylated CD44, which contains a saccharide structure of Galb1-3(Neu5Aca2-6)GlcNAcb1-4Galb1-4Glcb of epitope. Also provided is an antibody which specifically recognizes the antigen, and it is found through immunomagnetic bead experiments on clinical samples that the EM2D9-MB positive detection rate of a detecting method using the antibody to recognize the antigen GAB31 is obviously higher than that of a conventional cast-off cell microscopic examination method.