首页> 外国专利> COMBINATION THERAPY OF CANCER WITH ANTI-ENDOGLIN ANTIBODIES AND ANTI-PROGRAMMED DEATH RECEPTOR AGENTS

COMBINATION THERAPY OF CANCER WITH ANTI-ENDOGLIN ANTIBODIES AND ANTI-PROGRAMMED DEATH RECEPTOR AGENTS

机译:癌症与抗内皮糖蛋白抗体和抗编程死亡受体代理的联合治疗

摘要

The present application relates to an anti-endoglin antibody in combination with an anti-PD-1 antibody. The present application relates to an anti-endoglin antibody in combination with an anti-PD-L1 antibody. The present application relates to an anti-endoglin antibody in combination with an anti-PD-1 antibody and an anti-PD-L1 antibody. The present application also relates to an anti-endoglin antibody in combination with Nivolumab, Pidilizumab and PDR001, Pembrolizumab, BMS-936559, Avelumab or Atezolizumab. Another aspect relates to the use of the combinations of the antibodies for use in treating cancers and metastases thereof.
机译:本申请涉及与抗PD-1抗体组合的抗内啡肽抗体。本申请涉及与抗PD-L1抗体组合的抗内啡肽抗体。本申请涉及与抗PD-1抗体和抗PD-L1抗体组合的抗内啡肽抗体。本申请还涉及与尼伏鲁单抗,吡地珠单抗和PDR001,派姆单抗,BMS-936559,阿夫单抗或阿妥索单抗联合的抗endoglin抗体。另一个方面涉及抗体的组合用于治疗癌症及其转移的用途。

著录项

  • 公开/公告号WO2018187158A1

    专利类型

  • 公开/公告日2018-10-11

    原文格式PDF

  • 申请/专利权人 TRACON PHARMACEUTICALS INC.;

    申请/专利号WO2018US25207

  • 发明设计人 THEUER CHARLES;HAWINKELS LUKAS;

    申请日2018-03-29

  • 分类号A61K39/395;A61K45/06;A61K51/10;C07K16/28;C07K16/30;C12P21/08;

  • 国家 WO

  • 入库时间 2022-08-21 12:42:18

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