首页> 外国专利> Novel Sesquiterpenic derivative preparation method thereof and pharmaceutical composition for use in preventing or treating bone diseases containing the same as an active ingredient

Novel Sesquiterpenic derivative preparation method thereof and pharmaceutical composition for use in preventing or treating bone diseases containing the same as an active ingredient

机译:一种新的倍半萜衍生物的制备方法和用于预防或治疗含有其活性成分的药物的药物组合物

摘要

The present invention relates to a novel sesquiterpene derivative, a preparing method for the same, and a pharmaceutical composition including the same as an active ingredient for preventing or treating bone diseases. According to the present invention, the compound being the novel sesquiterpene derivative represented by the chemical formula 1 and stereoisomers of the same or pharmaceutically acceptable salt of the same have excellent osteoclast formation inhibiting capabilities and suppress the destruction or absorption of bone tissues accordingly, thereby making the pharmaceutical composition including the same as an active ingredient for preventing or treating bone diseases useful.
机译:本发明涉及一种新的倍半萜衍生物,其制备方法以及包含其的药物组合物作为预防或治疗骨病的活性成分。根据本发明,该化合物是由化学式1表示的新型倍半萜衍生物及其相同或异构体的立体异构体,具有优异的破骨细胞形成抑制能力,并因此抑制了骨组织的破坏或吸收。包含与作为预防或治疗骨疾病的有效成分相同的药物组合物。

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