.Mouse model and its manufacturing method having characterized the adjusted polarity of Macrophage

摘要

The present invention is to propose a method of mouse model for studying the functions and characteristics of polarized macrophages in the body when diseases or infections are induced using macrophage activation or a polarized mouse model. More specifically, the M1 macrophage mouse model was stimulated with either Lipopolysaccharide (0.5-5 μg / kg) and IFN gamma (0.5-5 μg / kg) to induce the polarity of the papain macrophages in the mouse model, This is presented as a method of making a mouse model that can be applied to studies on the function and characteristics of macrophages acting upon induction.