首页> 外国专利> 5-Hydroxytryptamine receptor 2B Y A use of 5-Hydroxytryptamine receptor 2B and neuropeptide Y as a marker for predicting differentiation of stem cells

5-Hydroxytryptamine receptor 2B Y A use of 5-Hydroxytryptamine receptor 2B and neuropeptide Y as a marker for predicting differentiation of stem cells

机译:5-羟色胺受体2B Y 5-羟色胺受体2B和神经肽Y作为预测干细胞分化的标志物的用途

摘要

The present invention discloses the use of 5-Hydroxytryptamine receptor 2B (HTR2B) and neuropeptide Y as stem cell differentiation prediction markers, and more specifically, to a stem cell differentiation prediction including a substance for measuring mRNA expression or protein expression of HTR2B gene A method for predicting the differentiation of stem cells using the marker marker composition; Or neuropeptide Y gene mRNA expression or protein expression, and a method for predicting the differentiation of stem cells using the marker composition. The present invention confirms that HTR2B and neuropeptide Y can be used as a stem cell differentiation prediction marker. Thus, it is possible to predict the differentiation into various cardiac cells or neurons in various undifferentiated stem cells, The possibility of using undifferentiated stem cells as a selective cell therapy agent can be provided.
机译:本发明公开了5-羟色胺受体2B(HTR2B)和神经肽Y作为干细胞分化预测标志物的用途,更具体地说,涉及用于测定HTR2B基因的mRNA表达或蛋白质表达的物质的干细胞分化预测方法。用于使用标记标记组合物预测干细胞的分化;或神经肽Y基因的mRNA表达或蛋白质表达,以及一种使用标记物成分预测干细胞分化的方法。本发明证实HTR2B和神经肽Y可以用作干细胞分化预测标记。因此,可以预测在各种未分化的干细胞中向各种心脏细胞或神经元的分化。可以提供使用未分化的干细胞作为选择性细胞治疗剂的可能性。

著录项

  • 公开/公告号KR101904677B1

    专利类型

  • 公开/公告日2018-10-04

    原文格式PDF

  • 申请/专利权人 가톨릭대학교 산학협력단;

    申请/专利号KR20170178496

  • 发明设计人 김용구;김명신;권아름;

    申请日2017-12-22

  • 分类号C12Q1/68;C12N5/073;C12N5/077;C12N5/0775;C12N5/0793;G01N33/569;

  • 国家 KR

  • 入库时间 2022-08-21 12:37:02

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