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PDE5 INHIBITORS AND LEUCINE OR A LEUCINE METABOLITE FOR USE IN THE TREATMENT OF DIABETES
PDE5 INHIBITORS AND LEUCINE OR A LEUCINE METABOLITE FOR USE IN THE TREATMENT OF DIABETES
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机译:PDE5抑制剂和亮氨酸或亮氨酸代谢产物,用于治疗糖尿病
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摘要
Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions comprise a combination of a PDE 5 inhibitor, such as sildenafil or icariin, and resveratrol, and a branched amino acid such as leucine, or its metabolite.
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