首页> 外国专利> NOVEL BIOMARKER FOR DIAGNOSING RESISTANCE TO ANTICANCER AGENT FOR BILIARY TRACT CANCER AND USE THEREOF

NOVEL BIOMARKER FOR DIAGNOSING RESISTANCE TO ANTICANCER AGENT FOR BILIARY TRACT CANCER AND USE THEREOF

机译:新型抗生物标志物,可用于抗癌药物对抗癌药物的诊断

摘要

The present invention provides a novel molecule marker for resistance to an anticancer agent for biliary tract cancer, and diagnostic and therapeutic uses thereof. The marker, according to the present invention, shows significantly increased expression in an anticancer agent-resistant biliary tract cancer cell line compared to a non-anticancer agent-resistant biliary tract cancer cell line. By inhibiting the expression of protein in the marker according to the present invention, sensitivity of anticancer agent-resistant biliary tract cancer to the anticancer agent can be increased.
机译:本发明提供了对胆道癌抗癌剂具有抗性的新型分子标记,及其诊断和治疗用途。与非抗癌剂抗性胆道癌细胞系相比,根据本发明的标记在抗癌剂抗性胆道癌细胞系中显示出显着增加的表达。通过抑制根据本发明的标志物中蛋白质的表达,可以提高抗癌剂耐药性胆道癌对抗癌剂的敏感性。

著录项

  • 公开/公告号EP3309551A4

    专利类型

  • 公开/公告日2019-01-02

    原文格式PDF

  • 申请/专利权人 COWELL BIODIGM CO. LTD.;

    申请/专利号EP20160807886

  • 发明设计人 SONG SI YOUNG;PARK SOO BIN;

    申请日2016-06-16

  • 分类号G01N33/574;C12Q1/68;C12N15/115;A61K31/517;A61K31/7088;A61K39/395;

  • 国家 EP

  • 入库时间 2022-08-21 12:28:16

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