首页> 外国专利> PRODUCTION METHOD FOR EASY-TO-TAKE SOLID PREPARATION (NUCLEATED TABLET), AND EASY-TO-TAKE SOLID PREPARATION

PRODUCTION METHOD FOR EASY-TO-TAKE SOLID PREPARATION (NUCLEATED TABLET), AND EASY-TO-TAKE SOLID PREPARATION

机译:易取固体制剂(核片剂)的生产方法及易取固体制剂

摘要

The purpose of present invention to provide a method for the production of an easy-to-take solid preparation, which is mainly characterized in that an outer layer-forming processing to provide an easy-to-take property is simply performed in a dry process without going through a wet condition so as to make the formed outer layer thicker; the easy-to-take solid preparation and the like. The present invention relates to a dry-process method for the production of an easy-to-take solid preparation wherein an inner core tablet is coated with a compression-molded outer layer-forming agent comprising a gelling agent that will show slipperiness when it is brought into contact with water, comprising loading separately or simultaneously the inner core tablet and powder of the outer layer-forming agent to a mortar inner surface, the bottom end surface of an upper-pestle, and the top end surface of a lower-pestle, and subsequently compression-molding them; a powder composition for coating a solid preparation for use in the above method, which comprises the water-soluble polymer and water-soluble sugar or sugar alcohol
机译:本发明的目的是提供一种制备易于摄取的固体制剂的方法,其主要特征在于,在干燥过程中简单地进行提供易摄取性的外层形成处理。无需经过潮湿条件,以使形成的外层更厚;易于服用的固体制剂等。本发明涉及一种生产易于摄取的固体制剂的干法方法,其中在内核片上涂有压缩成型的外层形成剂,所述形成剂包括当形成时会显示出滑爽性的胶凝剂。使与水接触,包括将内芯片剂和外层形成剂的粉末分别或同时装载至研钵内表面,上杵的底端表面和下杵的上端表面,然后将其压缩成型;用于上述方法的用于涂覆固体制剂的粉末组合物,其包含水溶性聚合物和水溶性糖或糖醇

著录项

  • 公开/公告号EP3315115A4

    专利类型

  • 公开/公告日2019-03-06

    原文格式PDF

  • 申请/专利权人 DAICEL CORPORATION;

    申请/专利号EP20160817907

  • 申请日2016-06-28

  • 分类号A61J3/10;A61J3/06;A61K9/26;A61K47/10;A61K47/12;A61K47/14;A61K47/26;A61K47/36;A61K47/38;A61K47/42;B30B11/34;A61K9/20;A61K9/28;

  • 国家 EP

  • 入库时间 2022-08-21 12:28:03

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