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BENZHYDROL DERIVATIVES FOR THE MANAGEMENT OF CONDITIONS RELATED TO HYPOXIA INDUCIBLE FACTORS

机译:苯并吡咯衍生物用于治疗与缺氧易感因素有关的疾病

摘要

This disclosure relates to benzhydrol derivatives for managing conditions related to the Hypoxia Inducible Factor (HIF) pathway such as uses in treating cancer. In certain embodiment, the disclosure contemplates compounds and pharmaceutical compositions. In certain embodiment, the disclosure contemplates compounds disclosed herein as prodrugs, optionally substituted with one or more substituents, derivatives, or salts thereof.
机译:本公开涉及用于处理与低氧诱导因子(HIF)途径有关的状况的苯氢衍生物,例如用于治疗癌症。在某些实施方案中,本发明涵盖化合物和药物组合物。在某些实施方案中,本公开内容考虑将本文公开的化合物作为前药,任选地被一个或多个取代基,其衍生物或盐取代。

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